Chun-Tao Che, Ph.D.Joanna Burdette

Norman R. Farnsworth Professor of Pharmacognosy
Department of Medicinal Chemistry and Pharmacognosy

University of Illinois at Chicago
College of Pharmacy
833 South Wood Street (M/C 781)
Chicago IL 60612-7231

Office: 323 PHARM
Office Phone: 312-996-5234
Lab: 274/294 PHARM
Fax Number: 312-996-7107
E-mail address:


The Chinese University of Hong Kong, B.Sc. (Biology), 1975
The Chinese University of Hong Kong, M.Phil. (Biochemistry), 1977
The University of Illinois at Chicago, Ph.D. (Pharmacognosy), 1982

Previous Positions Held:

Postdoctoral Chemist, Ludwig Institute for Cancer Research, Toronto, Canada (1982-1984)
Research Associate/Research Assistant Professor, Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (1984-1991)
Associate Professor, Department of Chemistry, Hong Kong University of Science and Technology (1991-1998)
Professor and Director, School of Chinese Medicine, The Chinese University of Hong Kong (1998-2010)

Research Interests:

Interested in natural drugs and Chinese medicine, including:

  1. Natural products chemistry: isolation, characterization, and structural elucidation of secondary metabolites from medicinal plants and other natural sources
  2. Biologically active natural substances
  3. Chemical/biological standardization and quality assessment of herbal drugs and herb-based preparations
  4. Development of analytical techniques for herbal drug analysis
  5. Development of evidence-based Chinese medicine and other natural products

Selected Publications of Dr CT Che (2014-2015):

  1. M. Zhao, X. Zhang, Y. Wang, M. Huang, J.-A. Duan, T. Gödecke, K.M. Szymulanska-Ramamurthy, Z. Yin and C.T. Che, Germacranes and m-Menthane from Illicium lanceolatum. Molecules 19: 4326-4337, 2014.
  2. C. M. Witt, M. Aickin, D. Cherkin, C.T. Che, C. Elder, A. Flower, R. Hammerschlag, J.-P. Liu, L. Lao, S. Phurrough, C. Ritenbaugh, L.H. Rubin, R. Schnyer, P.M. Wayne, S.R. Withers, Z.X. Bian, J. Young and B.M. Berman, Effectiveness guidance document (EGD) for Chinese medicine trials: A consensus document. Trials 15: 169, 2014. [DOI:10.1186/1745-6215-15-169]
  3. D.-T. Xie, Y.-Q. Wang, Y. Kang, Q.-F. Hu, N.-Y. Su, J.-M. Huang, C.T. Che and J.-X. Guo, Microwave- assisted extraction of bioactive alkaloids from Stephania sinica. Sep. Purif. Techol., 130: 173-181, 2014.
  4. F.W.K. Cheung, A.W.N. Leung, W.K. Liu and C.T. Che, Tyrosinase inhibitory activity of a glucosylated hydroxystilbene in mouse Melan-a melanocytes. J. Nat. Prod. 77: 1270-1274, 2014.
  5. R. Feng, X. Zhou, X.S. Tan, P.M. Or, T. Hu, J. Fu, J.Y. Ma, M. Huang, C.Y. He, J.G. Shi, C.T. Che, J.H Yeung and Y. Wang, In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxy-2,3,5-trimethoxyxanthone purified from Halenia elliptica D.Don. Chem. Biol. Interact. 210: 12-19, 2014.
  6. Z. Lu, D. Liang, M. Zhao, C.T. Che and R. Chen, Carrier-free, pure resveratrol micro-nanoribbon: Simple preparation and enhanced bioactivity. Mater. Focus 3: 1-5, 2014.
  7. M.M. Onakpa, M. Zhao, T.Goedecke, W.-L. Chen, C.T. Che, B.D. Santarsiero, S.M. Swanson and A.I. Uzoma, Cytotoxic 9βH- and 17-nor-9βH-pimarane diterpenes from the tuber of Icacina trichantha. Chem. Biodiversity 11: 1914-1922, 2014.
  8. M. Zhou, M.M. Miao, G. Du, X.N. Li, S.Z. Shang, W. Zhao, Z.H. Liu, G.Y. Yang, C.T. Che, Q.F. Hu and X.M. Gao, Aspergillines A-E, highly oxygenated hexacyclic indole-tetrahydrofuran-tetramic acid derivatives from Aspergillus versicolor, Org Lett. 16: 5016-5019, 2014.
  9. Y. Zhang, T.-Y. Diao, L. Wang, C.T. Che, M.S Wong, Protective effects of water fraction of Fructus Ligustri Lucidi extract against hypercalciuria and trabecular bone deterioration in experimentally type 1 diabetic mice. J. Ethnopharmacol. 158: 239-245, 2014.
  10. G. Liu, R.R. Zheng, Z.W. Liu, W.J. Wang, G.Q. Li, C.L. Fan, X.Q. Zhang, W.C. Ye and C.T. Che, Enantiomeric chromones from Harrisonia perforatePhytochem Lett. 10: 295-299, 2014.
  11. Y. Ma, C. Jiang, N. Yao, Y. Li, Qi. Wang, S. Fang; X. Shang, M. Zhao, C.T. Che, Y. Ni, Z. Yin,  Antihyperlipidemic effect of Cyclocarya paliurus extract and inhibition of apolipoprotein B48 overproduction in hyperlipidemic mice. J. Ethnopharmacol. 166: 286-296, 2015.
  12. M. Zhao, M. M.Onakpa, W.-L. Chen, B.D. Santarsiero, S.M. Swanson, J.E. Burdette, I.U. Asuzu and C.T. Che, 17-Norpimaranes and (9βH)-17-norpimaranes from the tuber of Icacina trichantha. J. Nat. Prod. 78: 789-796, 2015.
  13. M. Zhou, K. Zhou, X.M. Gao, Z.Y. Jiang, J.J. Lv, Z.H. Liu, G.Y. Yang, M.M. Miao, C.T. Che, C.T. and Q.F. Hu, Fistulains A and B, novel bischromones from the bark of Cassia fistula and their activities. Org. Lett. 17: 2638-2641, 2015.
  14. M. Zhao, M.M. Onakpa, B.D. Santarsiero, X.J. Huang, X.Q. Zhang, J. Chen, J.J. Cheng, R. Longnecker and C.T. Che, Icacinlactone H and Icacintrichantholide from the tuber of Icacina trichantha. Org. Lett. 17: 3834-3837, 2015
  15. X. Deng, J. Yu, M. Zhao, B. Zhao, X. Xue, C.T. Che, J. Meng, S. Wang, Quality assessment of crude and processed ginger by high-performance liquid chromatography with diode array detection and mass spectrometry combined with chemometrics. J. Sep. Sci. 38: 2945-2952, 2015.
  16. M. Zhao, M.M. Onakpa, B.D. Santarsiero, W.L. Chen, K.M. Szymulanska-Ramamurthy, S.M. Swanson, J.E. Burdette and C.T. Che, (9βH)-pimaranes and derivatives from the tuber of Icacina trichantha. J. Nat. Prod. 78: 2731-2737, 2015.
  17. C.T. Che and M.-S. Wong, Ligustrum lucidum and its constituents: A mini-review on the anti-osteoporosis potential. Nat. Prod. Commun. 10: 2189-2194, 2015.
  18. Z.Q. Yin, S.L. Yu, Y.J. Wei, L. Ma, Z.F. Wu, L. Wang, Q.W. Zhang, M. Zhao, W.C. Ye, C.T. Che and J. Zhang, C21 steroidal glycosides from Cynanchum stauntonii induce apoptosis in HepG2 cells. Steroids 106: 55-61, 2016.
  19. O.O. Johnson, M. Zhao, J. Gunn, B. Santarsiero, Z. Yin, G. Ayoola, H.A.B. Coker, C.T. Che, α-Glucosidase inhibitory prenylated anthranoids from Harungana madagascariensis. J. Nat. Prod. 79: 224-229, 2016.


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